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BDBM289456 (S)-1-(4-(6-amino-5- (trifluoromethyl)- pyridin-3-yl)-1- (bicyclo[1.1.1]pentan- 1-yl)-1H-imidazol-2- yl)ethan-1-ol::US10093664, Example 33

SMILES: C[C@H](O)c1nc(cn1C12CC(C1)C2)-c1cnc(N)c(c1)C(F)(F)F

InChI Key: InChIKey=GBIJQSUOJCVWTL-GMSXMYEBSA-N

Data: 1 Kd

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289456   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase kinase kinase 12


(Homo sapiens)
BDBM289456
PNG
((S)-1-(4-(6-amino-5- (trifluoromethyl)- pyridin-3-...)
Show SMILES C[C@H](O)c1nc(cn1C12CC(C1)C2)-c1cnc(N)c(c1)C(F)(F)F
Show InChI InChI=1S/C16H17F3N4O/c1-8(24)14-22-12(7-23(14)15-3-9(4-15)5-15)10-2-11(16(17,18)19)13(20)21-6-10/h2,6-9,24H,3-5H2,1H3,(H2,20,21)/t8-,9?,15?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 9.70n/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK...


US Patent US10093664 (2018)

More data for this
Ligand-Target Pair