BDBM289495 1-(4-(6-amino-5-(tri- fluoromethyl)pyridin-3- yl)-1-(3-morpholino- bicyclo[1.1.1]pentan-1- yl)-1H-imidazol-2-yl)- 2-methylpropan-1-ol::US10093664, Example 67

SMILES CC(C)C(O)c1nc(cn1C12CC(C1)(C2)N1CCOCC1)-c1cnc(N)c(OC(F)(F)F)c1

InChI Key InChIKey=KAUITHCNCVKECM-UHFFFAOYSA-N

Data  1 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289495   

TargetMitogen-activated protein kinase kinase kinase 12(Homo sapiens (Human))
The University Of Texas System

US Patent
LigandPNGBDBM289495(1-(4-(6-amino-5-(tri- fluoromethyl)pyridin-3- yl)-...)
Affinity DataKd:  0.110nMAssay Description:The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB