BDBM289847 (4R)-1′-((1-(3-amino-1H-indazol-6-yl)ethyl)-L-phenylalanyl)-6-chlorospiro[benzo[d][1,3]oxazine-4,3′-pyrrolidin]-2(1H)-one dihydrochloride::US10093683, Example 224
SMILES CC(N[C@@H](Cc1ccccc1)C(=O)N1CCC2(C1)OC(=O)Nc1ccc(Cl)cc21)c1ccc2c(N)n[nH]c2c1
InChI Key
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 289847
Affinity DataKi: 8.75E+3nM ΔG°: -6.90kcal/molepH: 7.4 T: 2°CAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair