BDBM289859 1-{6-[5-(2H-Pyrazol-3-yl)-pyridin-2- yloxy]-naphthalen-2-ylmethyl}- azetidine-3-carboxylic acid amide::US9573957, Example 2

SMILES NC(=O)C1CN(Cc2ccc3cc(Oc4ccc(cn4)-c4ccn[nH]4)ccc3c2)C1

InChI Key InChIKey=BVIFPUYVEFLSNH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289859   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289859(1-{6-[5-(2H-Pyrazol-3-yl)-pyridin-2- yloxy]-naphth...)
Affinity DataIC50:  0.460nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent