BDBM289915 (8-{6-[5-(2H-Pyrazol-3-yl)-pyridin- 2-yloxy]-quinolin-2-ylmethyl}-3,8- diaza-bicyclo[3.2.1]oct-3-yl)-(S)- tetrahydro-furan-2-yl-methanone::US9573957, Example 55

SMILES O=C([C@@H]1CCCO1)N1CC2CCC(C1)N2Cc1ccc2cc(Oc3ccc(cn3)-c3ccn[nH]3)ccc2n1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289915   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289915((8-{6-[5-(2H-Pyrazol-3-yl)-pyridin- 2-yloxy]-quino...)
Affinity DataIC50:  1.70nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent