BDBM289935 (S)-2-Methoxy-1-[4-(2-{6-[5-(2H- pyrazol-3-yl)-pyridin-2-yloxy]- benzofuran-3-yl}-ethyl)-piperazin- 1-yl]-propan-1-one::US9573957, Example 75

SMILES CO[C@@H](C)C(=O)N1CCN(CCc2coc3cc(Oc4ccc(cn4)-c4ccn[nH]4)ccc23)CC1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289935   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289935((S)-2-Methoxy-1-[4-(2-{6-[5-(2H- pyrazol-3-yl)-pyr...)
Affinity DataIC50:  0.880nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent