BDBM289951 2-Hydroxy-1-(4-{6-[4-(2H-pyrazol- 3-yl)-phenoxy]-imidazo[1,2-a]pyridin- 2-ylmethyl}-piperazin-1-yl)-ethanone::US9573957, Example 86

SMILES OCC(=O)N1CCN(Cc2cn3cc(Oc4ccc(cc4)-c4cnc[nH]4)ccc3n2)CC1

InChI Key InChIKey=FKURZCIHJXPHPW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289951   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289951(2-Hydroxy-1-(4-{6-[4-(2H-pyrazol- 3-yl)-phenoxy]-i...)
Affinity DataIC50:  0.790nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent