BDBM289982 1-[4-({6-[5-(2H-Pyrazol-3-yl)-pyridin- 2-yloxy]-benzofuran-3-ylmethyl}- amino)-piperidin-1-yl]-ethanone::US9573957, Example 108

SMILES CC(=O)N1CCC(CC1)NCc1coc2cc(Oc3ccc(cn3)-c3ccn[nH]3)ccc12

InChI Key InChIKey=CEPZLVCPIJTAQQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289982   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289982(1-[4-({6-[5-(2H-Pyrazol-3-yl)-pyridin- 2-yloxy]-be...)
Affinity DataIC50:  0.710nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent