BDBM289996 3-Hydroxy-3-methyl-1-(4-{6- [5-(2H-pyrazol-3-yl)-pyridin-2- yloxy]-quinolin-2-ylmethyl}- piperazin-1-yl)-butan-1-one::US9573957, Example 122

SMILES CC(C)(O)CC(=O)N1CCN(Cc2ccc3cc(Oc4ccc(cn4)-c4ccn[nH]4)ccc3n2)CC1

InChI Key InChIKey=DHFRDGGMJJOCFZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289996   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM289996(3-Hydroxy-3-methyl-1-(4-{6- [5-(2H-pyrazol-3-yl)-p...)
Affinity DataIC50:  3.90nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent