BDBM290017 (1-Hydroxy-cyclobutyl)-(4-{6- [5-(2H-pyrazol-3-yl)-pyridin-2- yloxy]-quinolin-2-ylmethyl}- piperazin-1-yl)-methanone::US9573957, Example 143

SMILES OC1(CCC1)C(=O)N1CCN(Cc2ccc3cc(Oc4ccc(cn4)-c4ccn[nH]4)ccc3n2)CC1

InChI Key InChIKey=HJNZOYPBUFUHRJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 290017   

TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM290017((1-Hydroxy-cyclobutyl)-(4-{6- [5-(2H-pyrazol-3-yl)...)
Affinity DataIC50:  1.80nMpH: 7.5 T: 2°CAssay Description:The compounds of the invention are assessed for the ability to interact with human LTA4 hydrolase in an enzymatic assay that measures the ability of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent