BDBM290065 US9573961, Example 50
SMILES Cc1c2COC(=O)c2ccc1C1CN2CCCN(CC2CO1)C(=O)Cc1ccc(cc1)-n1cnnn1
InChI Key InChIKey=OCRUGTZBBSKLBA-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 290065
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 740nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair