BDBM290114 US9573961, Example 99
SMILES Cc1c(ccc(F)c1C#N)[C@@H]1CN2CCN(C[C@H]2CN1)C(=O)Cc1ccc(cc1)-n1cnnn1
InChI Key InChIKey=KLHDJZPXFSHZFA-XXBNENTESA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 290114
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 70nMpH: 7.4Assay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair