BDBM290203 US9573958, Compound 18

SMILES CC(C)C=C(C#N)C(=O)N1CCCC(C1)n1c2ccc(CN(C)[C@@H](C)C(C)(C)C)cc2[nH]c1=NC(=O)c1ccc(Cl)cc1

InChI Key InChIKey=NGGIQWZGTDAAJH-RNWBJFQOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 290203   

TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290203(US9573958, Compound 18)
Affinity DataIC50:  28nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent