BDBM290295 7-(Piperidin-4-yl)pyrazino[2′,3′:3,4]pyrazolo[1,5-a]pyrimidin-9(10H)-one hydrochloride::US10098883, Example 38::US10668071, Example 38

SMILES O=c1cc(C2CCNCC2)n2nc3nccnc3c2[nH]1

InChI Key InChIKey=HJPUROSFQNIPTE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 290295   

TargetPlasminogen [101-181](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM290295(7-(Piperidin-4-yl)pyrazino[2′,3′:3,4]p...)
Affinity DataIC50:  60nMAssay Description:The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasminogen [101-181](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM290295(7-(Piperidin-4-yl)pyrazino[2′,3′:3,4]p...)
Affinity DataIC50:  60nMpH: 7.0Assay Description:The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent