BDBM290407 (3R,4S)-3-amino-4-(3-boronopropyl)-1-((S)-pyrrolidine-2- carbonyl)pyrrolidine-3-carboxylic acid::US10098902, Example 43::US10603330, Example 43::US11389464, Example 43

SMILES N[C@]1(CN(C[C@@H]1CCCB(O)O)C(=O)C1CCCN1)C(O)=O

InChI Key InChIKey=OHNHSUQVNXSZCH-DZGIZQBRSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 290407   

TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290407((3R,4S)-3-amino-4-(3-boronopropyl)-1-((S)-pyrrolid...)
Affinity DataIC50: <250nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290407((3R,4S)-3-amino-4-(3-boronopropyl)-1-((S)-pyrrolid...)
Affinity DataIC50:  625nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290407((3R,4S)-3-amino-4-(3-boronopropyl)-1-((S)-pyrrolid...)
Affinity DataIC50:  625nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290407((3R,4S)-3-amino-4-(3-boronopropyl)-1-((S)-pyrrolid...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290407((3R,4S)-3-amino-4-(3-boronopropyl)-1-((S)-pyrrolid...)
Affinity DataIC50:  125nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290407((3R,4S)-3-amino-4-(3-boronopropyl)-1-((S)-pyrrolid...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent