BDBM29042 cambinol analog, 6b

SMILES Oc1ccc2ccccc2c1Cc1c([nH]c(=S)[nH]c1=O)-c1ccc(Br)cc1

InChI Key InChIKey=HWHNRRGQEQLDQM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 29042   

TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of St. Andrews

LigandPNGBDBM29042(cambinol analog, 6b)
Affinity DataIC50:  1.27E+4nMpH: 8.0 T: 2°CAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of St. Andrews

LigandPNGBDBM29042(cambinol analog, 6b)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of SIRT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of St. Andrews

LigandPNGBDBM29042(cambinol analog, 6b)
Affinity DataIC50: >9.00E+4nMAssay Description:Compounds were tested for inhibition of sirtuin (SIRT1 or SIRT2) using the human recombinant enzyme provided with the Fluor de Lys fluorescence-based...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed