BDBM291315 US9580432, Example 46

SMILES Nc1ncnc2n(cc(C(=O)Nc3nc4cc(Cl)ccc4o3)c12)C1CN(C1)C(=O)C=C

InChI Key InChIKey=CPRRKPCMKQHCKV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 291315   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM291315(US9580432, Example 46)
Affinity DataIC50:  3.27nMpH: 7.5Assay Description:With regard to the setting of the conditions for a method for measuring the inhibitory activity of a compound against BTK kinase activity in vitro, i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent