BDBM291320 US9580432, Example 51

SMILES CCN(CC)C\C=C\C(=O)N1CC[C@H](C1)n1cc(C(=O)Nc2nc3cc(Cl)ccc3o2)c2c(N)ncnc12

InChI Key InChIKey=ZSQXDUJXJCOVQV-FUTAKVPZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 291320   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM291320(US9580432, Example 51)
Affinity DataIC50:  31.1nMpH: 7.5 T: 2°CAssay Description:With regard to the setting of the conditions for a method for measuring the inhibitory activity of a compound against EGFR kinase activity in vitro, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM291320(US9580432, Example 51)
Affinity DataIC50:  1.48nMpH: 7.5Assay Description:With regard to the setting of the conditions for a method for measuring the inhibitory activity of a compound against BTK kinase activity in vitro, i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent