BDBM291368 4-[1-(4-Chlorophenyl)-2- (pyridin-3-yl)-1H-pyrrolo[2,3- c]pyridin-3-yl]piperidine-1- carboxamide; formic acid::US9580415, Example 2

SMILES NC(=O)N1CCC(CC1)c1c(-c2cccnc2)n(-c2ccc(Cl)cc2)c2cnccc12

InChI Key InChIKey=WZBSBFMKRPNPGH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 291368   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291368(4-[1-(4-Chlorophenyl)-2- (pyridin-3-yl)-1H-pyrrolo...)
Affinity DataIC50:  5.50E+3nMpH: 7.3 T: 2°CAssay Description:Compounds of the invention were tested for inhibition of the human ether a go-go related gene (hERG) K+ channel using IonWorks patch clamp electrophy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Proximagen

US Patent
LigandPNGBDBM291368(4-[1-(4-Chlorophenyl)-2- (pyridin-3-yl)-1H-pyrrolo...)
Affinity DataIC50: <1.00E+3nMAssay Description:All primary assays were performed at RT. with purified recombinantly expressed human SSAO. Enzyme was prepared essentially as described in Öhman et a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent