BDBM292102 3-(6,7-Dihydro-5H-pyrrolo[3,4-b]pyridin-2-yl)-2-oxoindoline-5-carbonitrile hydrochloride::US10100048, Example 5

SMILES O=C1Nc2ccc(cc2C1c1ccc2CNCc2n1)C#N

InChI Key InChIKey=PJTRJWLBKLLMIR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 292102   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM292102(3-(6,7-Dihydro-5H-pyrrolo[3,4-b]pyridin-2-yl)-2-ox...)
Affinity DataIC50: <100nMT: 2°CAssay Description:Compounds were tested for their ability to inhibit human Glycogen Synthase Kinase-3 beta (hGSK-3β) to phosphorylate biotin-YRRAAVPPSPSLSRHSSPHQ(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent