BDBM292468 (S)-2-chloro-N-(2-(ethylamino)propyl)-6-(5-phenylpyrazolo[1,5-a]pyrimidin-3-yl)isonicotinamide::US10100058, Example 124

SMILES CCN[C@@H](C)CNC(=O)c1cc(Cl)nc(c1)-c1cnn2ccc(nc12)-c1ccccc1

InChI Key InChIKey=DNPDRDDDCZITGJ-HNNXBMFYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 292468   

TargetCalcium/calmodulin-dependent protein kinase type II subunit delta(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM292468((S)-2-chloro-N-(2-(ethylamino)propyl)-6-(5-phenylp...)
Affinity DataEC50:  13.8nMAssay Description:CaMKII activity in neonatal rat ventricular myocytes (NRVM) was measured by monitoring the phosphorylation level of phospholamban using high-content ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCalcium/calmodulin-dependent protein kinase type II subunit delta(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM292468((S)-2-chloro-N-(2-(ethylamino)propyl)-6-(5-phenylp...)
Affinity DataIC50:  17.1nMAssay Description:The biochemical activity of recombinant CaMKIIδ was measured by monitoring the phosphorylation of a target peptide using Homogenous Time Resolve...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent