BDBM29295 triazole, 3m

SMILES COc1cccc(c1)-n1c(Sc2ncc(s2)[N+]([O-])=O)n[nH]c1=O

InChI Key InChIKey=GTWSJOWSBPIBAJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29295   

TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM29295(triazole, 3m)
Affinity DataIC50:  1.60E+4nMAssay Description:Compounds were tested for their ability to inhibit JNK1 phosphorylation of ATF2 in the Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM29295(triazole, 3m)
Affinity DataIC50:  118nMpH: 7.8 T: 0°CAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed