BDBM293358 US10106508, Compound I-27::US10106508, Example 27 N-(3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)-5-isopropoxy-2,3-dihydro-[1,4]dioxino[2,3-f]quinazolin-10-amine (I-27)
SMILES CC(C)Oc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c2OCCOc12
InChI Key InChIKey=FLDVQQIVLMTMPN-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 293358
TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Beijing Scitech-Mq Pharmaceuticals
US Patent
Beijing Scitech-Mq Pharmaceuticals
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:The sample compounds were dissolved in DMSO and diluted it to 500 μM concentration with DMSO and transferred to a dose plate. The compounds were...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Beijing Scitech-Mq Pharmaceuticals
US Patent
Beijing Scitech-Mq Pharmaceuticals
US Patent
Affinity DataIC50: <200nMAssay Description:The sample compounds were dissolved in DMSO and diluted it to 500 μM concentration with DMSO and transferred to a dose plate. The compounds were...More data for this Ligand-Target Pair