BDBM293789 3-({[(4R)-7-[(2,3-dihydro-1H-inden-5-yl)(methyl)amino]-3,4-::US10106534, Example 131

SMILES CN(Cc1ccc2CCCc2c1)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1

InChI Key InChIKey=HHRDCFZSYMXEIS-NRFANRHFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293789   

TargetLysine-specific demethylase 6B(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM293789(3-({[(4R)-7-[(2,3-dihydro-1H-inden-5-yl)(methyl)am...)
Affinity DataIC50:  5.50E+3nMT: 2°CAssay Description:The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM293789(3-({[(4R)-7-[(2,3-dihydro-1H-inden-5-yl)(methyl)am...)
Affinity DataIC50:  550nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent