BDBM293888 (S)-1-(3-Fluoro-2- methylphenyl)-N- hydroxy-3-(pyrimidin-5- yl)cyclopent-2- enecarboxamide::US10106535, Example 14::US9617259, 14

SMILES Cc1c(F)cccc1[C@@]1(CCC(=C1)c1cncnc1)C(=O)NO

InChI Key InChIKey=WIBZOPAYZTWUAG-KRWDZBQOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293888   

TargetHistone deacetylase 4(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM293888((S)-1-(3-Fluoro-2- methylphenyl)-N- hydroxy-3-(pyr...)
Affinity DataIC50:  30nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 4(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM293888((S)-1-(3-Fluoro-2- methylphenyl)-N- hydroxy-3-(pyr...)
Affinity DataIC50:  30nMAssay Description:5 μl of each solution of 1:20 diluted compound from above is transferred to a clear bottomed, black, 384-well assay plate using the Bravo or the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent