BDBM293909 (S)-3-(5-Fluoropyridin-3- yl)-N-hydroxy-1- phenylcyclopent-2- enecarboxamide::US10106535, Example 35::US9617259, 35

SMILES ONC(=O)[C@]1(CCC(=C1)c1cncc(F)c1)c1ccccc1

InChI Key InChIKey=WVTONWZRSXXBPD-KRWDZBQOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293909   

TargetHistone deacetylase 4(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM293909((S)-3-(5-Fluoropyridin-3- yl)-N-hydroxy-1- phenylc...)
Affinity DataIC50:  340nMAssay Description:2 μl (200×) of each diluted solution and each control (full activity: 100% DMSO alone or full inhibition 1 mM) is stamped into V-bottomed polypr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 4(Homo sapiens (Human))
Chdi Foundation

US Patent
LigandPNGBDBM293909((S)-3-(5-Fluoropyridin-3- yl)-N-hydroxy-1- phenylc...)
Affinity DataIC50:  340nMAssay Description:5 μl of each solution of 1:20 diluted compound from above is transferred to a clear bottomed, black, 384-well assay plate using the Bravo or the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent