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BDBM293954 US10106552, Compound 29

SMILES: Cn1cc(cn1)-c1c2CCC(C)(C)c2nc2sc(C(N)=O)c(N)c12

InChI Key: InChIKey=XYSRGOATRLXIRP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 293954   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM293954
PNG
(US10106552, Compound 29)
Show SMILES Cn1cc(cn1)-c1c2CCC(C)(C)c2nc2sc(C(N)=O)c(N)c12
Show InChI InChI=1S/C17H19N5OS/c1-17(2)5-4-9-10(8-6-20-22(3)7-8)11-12(18)13(15(19)23)24-16(11)21-14(9)17/h6-7H,4-5,18H2,1-3H3,(H2,19,23)
PDB

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UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 700n/an/an/an/an/an/a



Longevica Pharmaceuticals, Inc.

US Patent


Assay Description
To determine the IC50 of compounds of the invention, recombinant eEF2K was diluted in an assay buffer in the presence of calmodulin, a calcium-bindin...


US Patent US10106552 (2018)

More data for this
Ligand-Target Pair