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BDBM293965 US10106552, Compound 40

SMILES: Cc1ncsc1-c1c2CCC(C)(C)c2nc2sc(C(N)=O)c(N)c12

InChI Key: InChIKey=HANNNMVMEFJHGR-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 293965   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM293965
PNG
(US10106552, Compound 40)
Show SMILES Cc1ncsc1-c1c2CCC(C)(C)c2nc2sc(C(N)=O)c(N)c12
Show InChI InChI=1S/C17H18N4OS2/c1-7-12(23-6-20-7)9-8-4-5-17(2,3)14(8)21-16-10(9)11(18)13(24-16)15(19)22/h6H,4-5,18H2,1-3H3,(H2,19,22)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 400n/an/an/an/an/an/a



Longevica Pharmaceuticals, Inc.

US Patent


Assay Description
To determine the IC50 of compounds of the invention, recombinant eEF2K was diluted in an assay buffer in the presence of calmodulin, a calcium-bindin...


US Patent US10106552 (2018)

More data for this
Ligand-Target Pair