BDBM293983 (2S)-5-(2-(4-((3-(5-(2- Methoxyethoxy)-2- methylphenyl)benzo[b]thiophen- 5-yl)methoxy)phenyl)pent-3- yn-1-yl)-1H-tetrazole::US10106553, Compound 15

SMILES COCCOc1ccc(C)c(c1)-c1csc2ccc(COc3ccc(cc3)[C@H](Cc3nnn[nH]3)C#CC)cc12

InChI Key

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 293983   

TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM293983((2S)-5-(2-(4-((3-(5-(2- Methoxyethoxy)-2- methylph...)
Affinity DataEC50:  85nMT: 2°CAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMelanocortin receptor 4(Rattus norvegicus)TBA
LigandPNGBDBM293983((2S)-5-(2-(4-((3-(5-(2- Methoxyethoxy)-2- methylph...)
Affinity DataEC50:  26nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM293983((2S)-5-(2-(4-((3-(5-(2- Methoxyethoxy)-2- methylph...)
Affinity DataEC50:  85nMAssay Description:Agonist activity at human GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed