BDBM294043 US10106557, Compound 30
SMILES COC[C@H]1CCCN1c1ccc2N3[C@@H](COc2c1)[C@H](CNC(=O)c1ccc(Cl)s1)OC3=O
InChI Key InChIKey=RXCJPCHXBRDPDW-HFTRVMKXSA-N
Data 5 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 294043
Affinity DataKi: 9.71nMpH: 8.3Assay Description:The inhibitory activity on coagulation factor Xa activity in human was measured by using Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl). A buffer of 50...More data for this Ligand-Target Pair
Affinity DataKi: 16.2nMpH: 7.4Assay Description:The activity of the compound to be tested against prothrombinase was determined by the production of thrombin. In summary, 12.5 μL human factor ...More data for this Ligand-Target Pair
Affinity DataKi: 21.5nMpH: 8.3Assay Description:The inhibitory activity on coagulation factor Xa activity in rats was measured by using Tris-HCl buffer (50 mM, pH 8.3, 150 mM NaCl). A buffer of 50 ...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMpH: 7.4Assay Description:The inhibitory activity on human thrombin was determined by using a buffer (10 mM HEPES buffer, pH 7.4, 2 mM CaCl2). Appropriate wells in the Greiner...More data for this Ligand-Target Pair
Affinity DataKi: >2.00E+4nMpH: 8.2Assay Description:The inhibitory activity on human trypsin was determined by using buffer (50 mM Tris, pH 8.2, and 20 mM CaCl2). Appropriate wells in the Greiner 384 m...More data for this Ligand-Target Pair