BDBM294442 US9586959, Compound 36
SMILES CNC1CN(C1)c1nc2ncc(Cl)cc2c2ncnn12
InChI Key InChIKey=ZUESIEDHNAEKDJ-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 294442
Affinity DataIC50: >1.00E+8nMpH: 7.4 T: 2°CAssay Description:Each compound of the present invention prepared in the examples was prepared in DMSO into concentrations of 0.02, 0.06, 0.3 and 2 mM. 10 uL of the pr...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes measured after 30 mins b...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair