BDBM294500 1-[2-(2-{5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}ethyl)-1-methyl-1H-imidazol-4-yl]pyrrolidin-2-one::US9586970, 21

SMILES Cc1cc(C)n2nc(CCc3nc(cn3C)N3CCCC3=O)nc2n1

InChI Key InChIKey=NZEOSQVPQDWPJI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 294500   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM294500(1-[2-(2-{5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimi...)
Affinity DataIC50:  176nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent