BDBM294502 1-(2-{2-[3-Methyl-2-(trifluoromethyl)imidazo[1,2-b]pyridazin-6-yl]ethyl}-1-phenyl-1H-imidazol-4yl)pyrrolidin-2-one::US9586970, 23

SMILES Cc1c(nc2ccc(CCc3nc(cn3-c3ccccc3)N3CCCC3=O)nn12)C(F)(F)F

InChI Key InChIKey=NCBRUJGANGAGIJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 294502   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM294502(1-(2-{2-[3-Methyl-2-(trifluoromethyl)imidazo[1,2-b...)
Affinity DataIC50:  3.10nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent