BDBM294502 1-(2-{2-[3-Methyl-2-(trifluoromethyl)imidazo[1,2-b]pyridazin-6-yl]ethyl}-1-phenyl-1H-imidazol-4yl)pyrrolidin-2-one::US9586970, 23
SMILES Cc1c(nc2ccc(CCc3nc(cn3-c3ccccc3)N3CCCC3=O)nn12)C(F)(F)F
InChI Key InChIKey=NCBRUJGANGAGIJ-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 294502
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 3.10nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair