BDBM294940 2-{[2-Fluoro-6-(2H-1,2,3-triazol-2-yl)phenyl]carbonyl}-5-(5-methoxy-4,6-dimethylpyrimidin-2-yl)octahydropyrrolo[3,4-c]pyrrole::US9586962, Example 497
SMILES COc1c(C)nc(nc1C)N1CC2CN(CC2C1)C(=O)c1c(F)cccc1-n1nccn1
InChI Key InChIKey=IDIOEUCDVKLJSA-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 294940
Affinity DataKi: 7nM ΔG°: -11.1kcal/moleT: 2°CAssay Description:Chinese ovary cells (CHO) stably expressing human orexin 1 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco...More data for this Ligand-Target Pair
Affinity DataKi: 43nM ΔG°: -10.0kcal/moleT: 2°CAssay Description:HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...More data for this Ligand-Target Pair