BDBM295019 US10112922, Compound 9
SMILES COC\C=C\C(=O)N1CC[C@H](C1)n1nc(c(C(N)=O)c1N)-c1ccc(Oc2ccccc2)cc1
InChI Key InChIKey=HXVTZYMAJRTBSQ-KRZKXXONSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 295019
Affinity DataIC50: <100nMpH: 7.4Assay Description:The half inhibition concentrations (IC50 values) of the compounds disclosed herein on Btk were determined at both enzymatic level and cellular level:...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro activity in inhibiting ITK kinase was determined similar to that in respect of BTK kinase.The inhibitory activity of the compound of Example...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:In vitro activity in inhibiting ITK kinase was determined similar to that in respect of BTK kinase.The inhibitory activity of the compound of Example...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro activity in inhibiting ITK kinase was determined similar to that in respect of BTK kinase.The inhibitory activity of the compound of Example...More data for this Ligand-Target Pair