BDBM295076 3-(6-amino-5-(3- methylisoxazol-5- yl)pyridin-3-yl)-N-(1- methoxy-3-methylbutan- 2-yl)-4- methylbenzenesulfon- amide trifluoroacetic acid salt::US10112926, Example 19.11

SMILES COCC(NS(=O)(=O)c1ccc(C)c(c1)-c1cnc(N)c(c1)-c1cc(C)no1)C(C)C

InChI Key InChIKey=OLGSBNCYXOWJTG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 295076   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM295076(3-(6-amino-5-(3- methylisoxazol-5- yl)pyridin-3-yl...)
Affinity DataIC50:  320nMpH: 7.5 T: 2°CAssay Description:The luminescence-based ATP detection reagent KinaseGlo was obtained from Promega, (Cat. No. V6714, Lot No. 236161) through Catalys, Wallisellen, Swit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM295076(3-(6-amino-5-(3- methylisoxazol-5- yl)pyridin-3-yl...)
Affinity DataIC50: >1.00E+4nMpH: 7.5 T: 2°CAssay Description:The luminescence-based ATP detection reagent KinaseGlo was obtained from Promega, (Cat. No. V6714, Lot No. 236161) through Catalys, Wallisellen, Swit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM295076(3-(6-amino-5-(3- methylisoxazol-5- yl)pyridin-3-yl...)
Affinity DataIC50:  420nMpH: 7.5Assay Description:The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad, Calif., USA) (Cat. No. PV5099). The kit contains t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM295076(3-(6-amino-5-(3- methylisoxazol-5- yl)pyridin-3-yl...)
Affinity DataIC50:  56nMpH: 7.5Assay Description:The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad, Calif., USA) (Cat. No. PV5099). The kit contains t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 4-kinase beta(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM295076(3-(6-amino-5-(3- methylisoxazol-5- yl)pyridin-3-yl...)
Affinity DataIC50:  5.10E+3nMpH: 7.5 T: 2°CAssay Description:The luminescence-based ATP detection reagent KinaseGlo was obtained from Promega, (Cat. No. V6714, Lot No. 236161) through Catalys, Wallisellen, Swit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent