BDBM295243 US10112926, Example 104.15::rac-3-(6-amino-5-(2- methyloxazol-5- yl)pyridin-3-yl)-N-(2- hydroxypropyl)-4- methylbenzenesulfon- amide

SMILES CC(O)CNS(=O)(=O)c1ccc(C)c(c1)-c1cnc(N)c(c1)-c1cnc(C)o1

InChI Key InChIKey=BHUCXTFJLHAUGW-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 295243   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM295243(US10112926, Example 104.15 | rac-3-(6-amino-5-(2- ...)
Affinity DataIC50:  190nMpH: 7.5 T: 2°CAssay Description:The luminescence-based ATP detection reagent KinaseGlo was obtained from Promega, (Cat. No. V6714, Lot No. 236161) through Catalys, Wallisellen, Swit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM295243(US10112926, Example 104.15 | rac-3-(6-amino-5-(2- ...)
Affinity DataIC50: >1.00E+4nMpH: 7.5 T: 2°CAssay Description:The luminescence-based ATP detection reagent KinaseGlo was obtained from Promega, (Cat. No. V6714, Lot No. 236161) through Catalys, Wallisellen, Swit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM295243(US10112926, Example 104.15 | rac-3-(6-amino-5-(2- ...)
Affinity DataIC50:  5.00E+3nMpH: 7.5Assay Description:The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad, Calif., USA) (Cat. No. PV5099). The kit contains t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 4-kinase beta(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM295243(US10112926, Example 104.15 | rac-3-(6-amino-5-(2- ...)
Affinity DataIC50:  1.90E+3nMpH: 7.5 T: 2°CAssay Description:The luminescence-based ATP detection reagent KinaseGlo was obtained from Promega, (Cat. No. V6714, Lot No. 236161) through Catalys, Wallisellen, Swit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM295243(US10112926, Example 104.15 | rac-3-(6-amino-5-(2- ...)
Affinity DataIC50:  30nMpH: 7.5Assay Description:The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad, Calif., USA) (Cat. No. PV5099). The kit contains t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM295243(US10112926, Example 104.15 | rac-3-(6-amino-5-(2- ...)
Affinity DataIC50:  1.60E+3nMpH: 7.5 T: 2°CAssay Description:The luminescence-based ATP detection reagent KinaseGlo was obtained from Promega, (Cat. No. V6714, Lot No. 236161) through Catalys, Wallisellen, Swit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent