BDBM295275 6-((1- aminocyclopropyl) methylamino)-4-(6-tert- butylpyridin-2- ylamino)pyridazine-3- carboxamide::US10112928, Compound I-19

SMILES CC(C)(C)c1cccc(Nc2cc(NCC3(N)CC3)nnc2C(N)=O)n1

InChI Key InChIKey=RQZUSDZVAFYQJT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 295275   

TargetTyrosine-protein kinase SYK [360-635](Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM295275(6-((1- aminocyclopropyl) methylamino)-4-(6-tert- b...)
Affinity DataIC50:  135nMpH: 7.5Assay Description:SYK kinase assay is a standard kinase assay adapted to a 96 well plate format. This assay is performed in 96-well format for IC50 determination with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent