BDBM295407 (3R,4S)-1-(4-(1H-Pyrazol-4-yl)phenyl)-4-(hydroxymethyl)-3-((3-methoxyphenyl)amino) pyrrolidin-2-one::US10112929, Example 133

SMILES COc1cccc(N[C@@H]2[C@@H](CO)CN(C2=O)c2ccc(cc2)-c2cn[nH]c2)c1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 295407   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM295407((3R,4S)-1-(4-(1H-Pyrazol-4-yl)phenyl)-4-(hydroxyme...)
Affinity DataIC50:  5nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent