BDBM295407 (3R,4S)-1-(4-(1H-Pyrazol-4-yl)phenyl)-4-(hydroxymethyl)-3-((3-methoxyphenyl)amino) pyrrolidin-2-one::US10112929, Example 133
SMILES COc1cccc(N[C@@H]2[C@@H](CO)CN(C2=O)c2ccc(cc2)-c2cn[nH]c2)c1
InChI Key
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 295407
Affinity DataIC50: 5nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair