BDBM295793 US10112935, Compound 35AO

SMILES Cc1ccc(CC(=O)Nc2cccc(c2)-c2nnc(Nc3ccc4[nH]ncc4c3Cl)s2)nc1

InChI Key InChIKey=RXXJTXBACFSTGD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 295793   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM295793(US10112935, Compound 35AO)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Assays for ROCK inhibition were performed using the following protein constructs: glutathione S-transferase (GST)-tagged human ROCK1 catalytic domain...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM295793(US10112935, Compound 35AO)
Affinity DataIC50: >3.00E+4nMT: 2°CAssay Description:Assays for ROCK inhibition were performed using the following protein constructs: glutathione S-transferase (GST)-tagged human ROCK1 catalytic domain...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent