BDBM295906 US10112935, Compound 48Q

SMILES CC(=O)Nc1cc(cc(c1)-c1nnc(Nc2ccc3[nH]ncc3c2Cl)s1)C(=O)N1CCC(CC1)C(O)=O

InChI Key InChIKey=DGIMDKAMSXJSQX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 295906   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM295906(US10112935, Compound 48Q)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Assays for ROCK inhibition were performed using the following protein constructs: glutathione S-transferase (GST)-tagged human ROCK1 catalytic domain...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM295906(US10112935, Compound 48Q)
Affinity DataIC50:  8.00E+3nMT: 2°CAssay Description:Assays for ROCK inhibition were performed using the following protein constructs: glutathione S-transferase (GST)-tagged human ROCK1 catalytic domain...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent