BDBM295941 Butyl (4-chloro-1H-indazol-5-yl)(5-(3-(2-(4-fluorophenyl)acetamido)phenyl)-1,3,4-thiadiazol-2-yl)carbamate::US10112935, Example 53

SMILES CCCCOC(=O)N(c1nnc(s1)-c1cccc(NC(=O)Cc2ccc(F)cc2)c1)c1ccc2[nH]ncc2c1Cl

InChI Key InChIKey=NXBAFCXVEODPIR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 295941   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM295941(Butyl (4-chloro-1H-indazol-5-yl)(5-(3-(2-(4-fluoro...)
Affinity DataIC50: <1.00E+3nMT: 2°CAssay Description:Assays for ROCK inhibition were performed using the following protein constructs: glutathione S-transferase (GST)-tagged human ROCK1 catalytic domain...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM295941(Butyl (4-chloro-1H-indazol-5-yl)(5-(3-(2-(4-fluoro...)
Affinity DataIC50: >3.00E+4nMT: 2°CAssay Description:Assays for ROCK inhibition were performed using the following protein constructs: glutathione S-transferase (GST)-tagged human ROCK1 catalytic domain...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent