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BDBM296151 2-[4-[4-(2,2-dimethylpropoxy)-N- methylanilino]phenoxy]pyrido[3,4- d]pyrimidin-4-ol::US10112940, Example 75

SMILES: CN(c1ccc(OCC(C)(C)C)cc1)c1ccc(Oc2nc(O)c3ccncc3n2)cc1

InChI Key: InChIKey=BXVXQVVEVQBYAJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 296151   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific demethylase 4C


(Homo sapiens (Human))
BDBM296151
PNG
(2-[4-[4-(2,2-dimethylpropoxy)-N- methylanilino]phe...)
Show SMILES CN(c1ccc(OCC(C)(C)C)cc1)c1ccc(Oc2nc(O)c3ccncc3n2)cc1
Show InChI InChI=1S/C25H26N4O3/c1-25(2,3)16-31-19-9-5-17(6-10-19)29(4)18-7-11-20(12-8-18)32-24-27-22-15-26-14-13-21(22)23(30)28-24/h5-15H,16H2,1-4H3,(H,27,28,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10112940 (2018)

More data for this
Ligand-Target Pair