BindingDB logo
myBDB logout

BDBM296160 2-[4-(N,3,4- trimethylanilino)phenoxy]pyrido[3,4- d]pyrimidin-4-ol::US10112940, Example 83

SMILES: CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1ccc(C)c(C)c1

InChI Key: InChIKey=LEEOBDATXTXUKR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 296160   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific demethylase 4C


(Homo sapiens (Human))
BDBM296160
PNG
(2-[4-(N,3,4- trimethylanilino)phenoxy]pyrido[3,4- ...)
Show SMILES CN(c1ccc(Oc2nc(O)c3ccncc3n2)cc1)c1ccc(C)c(C)c1
Show InChI InChI=1S/C22H20N4O2/c1-14-4-5-17(12-15(14)2)26(3)16-6-8-18(9-7-16)28-22-24-20-13-23-11-10-19(20)21(27)25-22/h4-13H,1-3H3,(H,24,25,27)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/a25



Celgene Quanticel Research, Inc.

US Patent


Assay Description
The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...


US Patent US10112940 (2018)

More data for this
Ligand-Target Pair