BDBM29670 1-(3-{(E)-2-Cyano-2-[(furan-2-ylmethyl)-carbamoyl]-vinyl}-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)-piperidine-4-carboxylic acid amide::1-[3-[(E)-2-cyano-3-(2-furanylmethylamino)-3-oxoprop-1-enyl]-9-methyl-4-oxo-2-pyrido[1,2-a]pyrimidinyl]-4-piperidinecarboxamide::1-[3-[(E)-2-cyano-3-(2-furfurylamino)-3-keto-prop-1-enyl]-4-keto-9-methyl-pyrido[1,2-a]pyrimidin-2-yl]isonipecotamide::1-[3-[(E)-2-cyano-3-(furan-2-ylmethylamino)-3-oxidanylidene-prop-1-enyl]-9-methyl-4-oxidanylidene-pyrido[1,2-a]pyrimidin-2-yl]piperidine-4-carboxamide::1-[3-[(E)-2-cyano-3-(furan-2-ylmethylamino)-3-oxoprop-1-enyl]-9-methyl-4-oxopyrido[1,2-a]pyrimidin-2-yl]piperidine-4-carboxamide::MLS000580354::SMR000220631::cid_5881835

SMILES Cc1cccn2c1nc(N1CCC(CC1)C(N)=O)c(\C=C(/C#N)C(=O)NCc1ccco1)c2=O

InChI Key InChIKey=VGNRQGSUVJYKSW-SFQUDFHCSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29670   

TargetRunt-related transcription factor 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29670(1-(3-{(E)-2-Cyano-2-[(furan-2-ylmethyl)-carbamoyl]...)
Affinity DataIC50:  1.00E+5nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM29670(1-(3-{(E)-2-Cyano-2-[(furan-2-ylmethyl)-carbamoyl]...)
Affinity DataIC50:  1.00E+5nMpH: 7.4 T: 2°CAssay Description:This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay