BDBM296867 4-(5-(1-(2,5-Dimethylphenyl)-6,7-dimethyl-1,2,3,4-tetrahydroimidazo [1,2-a:5,4-b′]dipyridin-8-yl)pyrimidin-2-yl)morpholine::US10112944, Example 41

SMILES Cc1ccc(C)c(c1)N1CCCc2nc3c(C)c(C)c(cn3c12)-c1cnc(nc1)N1CCOCC1

InChI Key InChIKey=VDKYWHJPQBZBQG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 296867   

TargetTumor necrosis factor(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM296867(4-(5-(1-(2,5-Dimethylphenyl)-6,7-dimethyl-1,2,3,4-...)
Affinity DataIC50:  5.50E+3nMAssay Description:Test compounds serially diluted in DMSO were plated in an assay plate (Labcyte, Cat. #LP-0200) at final concentrations ranging from 0.004 μM to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent