BDBM297632 2-cyclopropyl-4-(4-(2- methoxyphenyl)piperidin-1- yl)-N-methyl-N-(2- morpholinoethyl)pyrido[3,4- d]pyrimidin-6-amine::US10118902, Example 134::US10118902, Example 194::US10584103, Example 134

SMILES COc1ccccc1C1CCN(CC1)c1nc(nc2cnc(cc12)N(C)CCN1CCOCC1)C1CC1

InChI Key InChIKey=BDGHZNUJQKZKQB-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 297632   

TargetNeurotensin receptor type 1(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM297632(2-cyclopropyl-4-(4-(2- methoxyphenyl)piperidin-1- ...)
Affinity DataEC50:  1.25E+3nMAssay Description:NTSR1 (NTR1) CHO cells are plated in 20 uL of assay media containing Ham's F12 supplemented with 10% fetal bovine serum and 0.4 mg/mL G418 at a c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM297632(2-cyclopropyl-4-(4-(2- methoxyphenyl)piperidin-1- ...)
Affinity DataEC50:  1.25E+3nMAssay Description:NTSR1 (NTR1) CHO cells are plated in 20 μL of assay media containing Ham's F12 supplemented with 10% fetal bovine serum and 0.4 mg/mL G418 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM297632(2-cyclopropyl-4-(4-(2- methoxyphenyl)piperidin-1- ...)
Affinity DataEC50:  1.25E+3nMAssay Description:NTSR1 (NTR1) CHO cells are plated in 20 μL of assay media containing Ham's F12 supplemented with 10% fetal bovine serum and 0.4 mg/mL G418 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM297632(2-cyclopropyl-4-(4-(2- methoxyphenyl)piperidin-1- ...)
Affinity DataEC50:  1.25E+3nMAssay Description:NTSR1 (NTR1) CHO cells are plated in 20 uL of assay media containing Ham's F12 supplemented with 10% fetal bovine serum and 0.4 mg/mL G418 at a c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent