BDBM297760 US10118918, Compound 42

SMILES O[C@@H](CNC(=O)c1cc(NC2COC2)ncn1)CN1CCc2ccccc12

InChI Key InChIKey=LLCIUGYFXSMFLR-HNNXBMFYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 297760   

TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM297760(US10118918, Compound 42)
Affinity DataIC50: >1.00E+4nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent