BDBM2978 Quinoxalinone deriv. 6w::ethyl 2-(2-cyclopropylethynyl)-7-fluoro-3-oxo-2-(trifluoromethyl)-1,2,3,4-tetrahydroquinoxaline-1-carboxylate

SMILES CCOC(=O)N1c2cc(F)ccc2NC(=O)C1(C#CC1CC1)C(F)(F)F

InChI Key InChIKey=LOXAGEOJXOMYDR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2978   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Central South University

Curated by ChEMBL
LigandPNGBDBM2978(Quinoxalinone deriv. 6w | ethyl 2-(2-cyclopropylet...)
Affinity DataIC50:  121nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandPNGBDBM2978(Quinoxalinone deriv. 6w | ethyl 2-(2-cyclopropylet...)
Affinity DataIC50:  121nMpH: 8.2 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed