BDBM298366 (S)-1-((2S)-1-(3-acetoxy-4,5-dimethoxybenzoyl)-4,4-difluoropyrrolidine-2-carbonyl)pyrrolidine-2-carbonitrile::US10125097, Example 15::US10611727, Example 15

SMILES COc1cc(cc(OC(C)=O)c1OC)C(=O)N1CC(F)(F)C[C@H]1C(=O)N1CCC[C@H]1C#N

InChI Key InChIKey=AOCAMLSIPXYBHW-GJZGRUSLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 298366   

TargetProlyl endopeptidase-like(Human)
Universitat De Barcelona

US Patent
LigandPNGBDBM298366((S)-1-((2S)-1-(3-acetoxy-4,5-dimethoxybenzoyl)-4,4...)
Affinity DataIC50:  5.60E+3nMAssay Description:POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Universitat De Barcelona

US Patent
LigandPNGBDBM298366((S)-1-((2S)-1-(3-acetoxy-4,5-dimethoxybenzoyl)-4,4...)
Affinity DataIC50:  5.60E+3nMAssay Description:POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent